The plasma contents of 5-hydroxytryptamine in anaphylactic shock

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Studies on the Relationship of 5-hydroxytryptamine and the Enterochromaffin Cell to Anaphylactic Shock in Mice

Protection against anaphylactic shock in mice by reserpine has been shown to be a delayed phenomenon, probably not dependent upon a direct effect of reserpine. The release and depletion of catechol amines by reserpine show little likelihood of being responsible for protection because these substances are in themselves protective against anaphylactic shock, while beta-TM 10, a drug which interfe...

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Anaphylactic shock is an unexpected, sudden and sometimes deadly event that attacks the patient in 75% of the cases without pre-existent history of allergy. In general, drugs, hymenopteric poisons and nutrients (according to the recent concept) are responsible. Beside the classical IgE-mediated anaphylactic shock there exists another anaphylactic shock, identical in its clinical picture and tre...

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The Mechanism of Anaphylactic Shock

1. The serum ferments are practically unaltered by a primary injection of foreign protein. 2. During the course of sensitization the injection of the antigen is followed by the mobilization of a non-specific protease which increases in rapidity and intensity as the maximum period of sensitization is reached. 3. Acute shock is accompanied by: (a) The instantaneous mobilization of a large amount ...

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ژورنال

عنوان ژورنال: Folia Pharmacologica Japonica

سال: 1956

ISSN: 0015-5691,1347-8397

DOI: 10.1254/fpj.52.851